We apply molecular simulation methods to study the dynamics of nucleosomes and elongation complexes in collaboration with Laboratory of transcription regulation and replication headed by Prof. V. Studitsky.
Current research topics:
- MD simulations and covariance analysis of nucleosome unfolding
- Molecular basics for asymmetric binding of H2A-H2B dimers in nucleosome
- Nucleosome and H1 interactions
- Molecular models of Pol II-nucleosome interactions
Some simulation results: